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TH07: the patented triple-combination drug candidate in Phase III development for androgenic alopecia

Our mission: to redefine the standard of care in hair loss

Androgenic alopecia has multiple biological causes, yet almost every treatment addresses only one. That is why results so often disappoint.

TH07 is different: a triple-combination, once-daily topical spray designed to target multiple growth pathways. It is now being evaluated in a randomized, placebo-controlled Phase III trial.

The Problem

Why monotherapies fall short

A disease with multiple causes, treated one cause at a time.

Androgenic alopecia is driven by multiple biological mechanisms at once. Most existing therapies address just one, so results fall short and many people give up on treatment. The problem was never the patient. It was the treatment.

  • Limited results, because single-agent treatments act on a single cause.
  • Hard to keep up, because greasy, twice-daily routines wear people down.
  • Systemic side effects of pill-based therapies
  • Millions still without a treatment that truly works.
Existing therapies: OnE pathway
Triple hair: Multiple pathways

Three pillars

Efficacy

Hair loss is caused by multiple growth pathways, and TH07 is designed to address them.

Safety

Scalp-targeted delivery, designed to keep the ingredients local to the scalp. Safety is being evaluated in the ongoing Phase III trial.

Compliance

A once-daily, non-greasy spray, designed to be easy to stay on.

THE HAIR LOSS MARKET
80 %

of men are affected
by androgenetic alopecia by age 70

Bhoyrul et al., Front Pharmacol 2026; Landells et al., J Cutan Med Surg 2025

$ 53.3 B

global alopecia market in 2025, projected to reach $100.6 billion by 2033; androgenetic alopecia accounts for 71% of it

Grand View Research, Alopecia Market Report, 2026

80 M

people in the United States are affected by androgenetic alopecia:
an estimated 50 million men and 30 million women

MedlinePlus, US National Library of Medicine, 2023

SOCIAL MEDIA

Latest insights and highlights

Insights from our research, milestones from our Phase 3 trial, and perspectives on why treating hair loss takes more than one pathway. See what the Triple Hair team is talking about.

Hair loss is often described as if the follicle simply “stops growing.”

The biology is more nuanced. In androgenetic alopecia, the changes happen gradually, across repeated hair-growth cycles. Understanding what is happening at the follicular level helps explain why AGA is a progressive condition and why the biology behind hair loss matters when studying potential treatments.

This serves as the basis for grasping the follicle and pursuing further research into answers. 

#AndrogeneticAlopecia#AGA#HairScience#HairBiology#HairLossResearch#Dermatology#TrichologyReference: Chen S, Li L, Ding W, Zhu Y, Zhou N. *Androgenetic Alopecia: An Update on Pathogenesis and Pharmacological Treatment.* Drug Des Devel Ther. 2025;19:7349–7363. doi:10.2147/DDDT.S542000.

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Triple Hair

Androgenetic alopecia affects both men and women.

Research suggests that up to 50% of women may experience androgenetic alopecia by age 70. Female pattern hair loss can differ in its presentation and characteristics, making it an important area of ongoing research.

Understanding who is affected, how hair loss presents, and the biology behind it helps build a clearer picture of androgenetic alopecia.

#TripleHair#AndrogeneticAlopecia#HairScience#HairLossResearch#WomensHealth#Dermatology#ClinicalResearch

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Triple Hair

We’re heading to Vienna for EADV Congress 2026, September 30–October 3.

We’re looking forward to connecting with dermatologists, researchers, and industry colleagues and exchanging perspectives on the evolving science of androgenic alopecia.

If you’ll be attending, let’s connect. See you in Vienna. 

#EADV2026#EADV#Dermatology#AndrogenicAlopecia#AGA#HairLossResearch#ClinicalResearch#TripleHair

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The most common form of hair loss, and still one of the most undertreated.

Androgenetic alopecia affects up to 80% of men and up to 50% of women by age 70 (Bhoyrul et al., 2026), with real consequences for confidence, identity, and quality of life.

One of the most common conditions in medicine remains one of the most under-researched. That gap deserves serious science.

#AndrogeneticAlopecia#HairLoss#DiseaseAwareness#QualityOfLife#Dermatology

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A recent review highlights that approximately 60% of patients using topical minoxidil may see no visible improvement. For a condition affecting millions of people, treatment response remains an important area of ongoing research. This is not about dismissing established therapies. It is about understanding where the evidence stands today, where limitations remain, and where scientific questions still need answers.

In research, an unmet need is often where the most important questions begin.

Reference: Bhoyrul B, et al. Expanding the therapeutic landscape of minoxidil for androgenetic alopecia.
Front Pharmacol. 2026;16:1718208.

#AndrogenicAlopecia#ClinicalResearch#HairLoss#AGA#Dermatology#PatientOutcomes

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Androgenic alopecia involves multiple biological processes. That complexity has led researchers to explore whether therapies with different mechanisms can be combined.

Published research has begun investigating combination approaches in AGA, including combinations of topical minoxidil and topical finasteride but combining therapies is only the beginning. Researchers still need to understand whether a combination is safe, effective, and supported by clinical evidence.

The science is evolving, and every study adds another piece to the picture.

#TripleHair#CombinationTherapy#AndrogenicAlopecia#AGA#HairLossResearch#ClinicalResearch#Dermatology#HairScience

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AGA is a complex biological condition, involving more than one process within the hair follicle raising an interesting research question: could therapies with different mechanisms be studied together? 

Published research has begun exploring combination approaches in AGA, including topical minoxidil and topical finasteride.

The goal of research is not to assume the answer, but to investigate it.

#TripleHair#HairScience#CombinationTherapy#AndrogenicAlopecia#AGA#HairLossResearch#ClinicalResearch#Dermatology

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What happens after a treatment is prescribed? Adherence is an important part of the real-world treatment equation.

For conditions that require ongoing management, factors such as treatment frequency, application experience, convenience, and expectations can all influence whether a regimen is maintained over time.

Clinical research can tell us whether an intervention works under study conditions. Understanding adherence helps us understand how treatment may be used in everyday life.

#TripleHair#HairLossResearch#AndrogenicAlopecia#AGA#Adherence#PatientExperience#ClinicalResearch#Dermatology#HealthScience

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Understanding androgenic alopecia

Androgenic alopecia is the most common form of hair loss, affecting a majority of men over the course of their lives and a significant number of women.

It is a progressive condition driven by genetics and hormonal factors, and it often begins earlier than many people expect. Because it advances gradually, changes can go unnoticed until they become visible.
Understanding the condition is the first step. If you are noticing changes, a conversation with a healthcare professional can help clarify what is happening and what options exist.

#HairLoss#AndrogenicAlopecia#MensHealth#HealthEducation#Dermatology

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Triple Hair

Our mission is simple to advance research in androgenic alopecia by developing innovative combination therapies grounded in science, rigorous clinical research, and a patient-centered approach.

At Triple Hair, we believe meaningful innovation begins with understanding the complexity of hair loss and continuing to explore new approaches through clinical investigation.

#TripleHair#Mission#ClinicalResearch#Biotech#HairLossResearch#AGA#Innovation

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LEARN MORE

Learn more about TH07

Triple Hair is advancing TH07 through late-stage clinical development. To learn more, or to discuss investment and partnership, get in touch.

info@triplehair.ca